Description

6,6-Dimethyl-8-(4-Morpholinopiperidin-1-Yl)-11-Oxo-6,11-Dihydro-5H-Benzo[B]Carbazole-3-Carbonitrile is a high-purity, advanced pharmaceutical intermediate designed for research and development. This compound is critical for medicinal chemists working on novel therapeutic agents, particularly in oncology and kinase inhibitor pathways. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions focused on drug discovery.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel small-molecule drug candidates.
• Kinase Inhibitor Research: Core scaffold for the development and optimization of potent and selective kinase inhibitors.
• Oncology Drug Discovery: Used in preclinical research for targeting specific cancer pathways and protein interactions.
• Medicinal Chemistry: Serves as a versatile precursor for structure-activity relationship (SAR) studies and lead optimization.
• Biochemical Assay Development: Employed as a reference standard or probe compound in high-throughput screening (HTS) and biochemical assays.
• Academic Research: Utilized in university and institutional labs for fundamental research in heterocyclic and carbazole chemistry.

Basic Information

Product Name	6,6-Dimethyl-8-(4-Morpholinopiperidin-1-Yl)-11-Oxo-6,11-Dihydro-5H-Benzo[B]Carbazole-3-Carbonitrile
CAS No.	1256577-71-5
Molecular Formula	C28H30N4O2
Molecular Weight	454.57 g/mol
Synonyms	8-(4-Morpholin-4-ylpiperidin-1-yl)-6,6-dimethyl-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile; 6,6-Dimethyl-8-(4-morpholinopiperidin-1-yl)-11-oxo-6,11-dihydro-5H-benzo[b]carbazole-3-carbonitrile; Benzo[b]carbazole-3-carbonitrile, 6,11-dihydro-6,6-dimethyl-8-(4-morpholinyl-1-piperidinyl)-11-oxo-; CAS 1256577-71-5
EINECS	Contact for details

Quality Control

Our 6,6-Dimethyl-8-(4-Morpholinopiperidin-1-Yl)-11-Oxo-6,11-Dihydro-5H-Benzo[B]Carbazole-3-Carbonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full traceability are provided for every shipment, supporting compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere if specified. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow solid
Identification (HPLC)	Conforms
Identification (MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.