Description

2,6-Difluoro-3-Methoxy-Dl-Phenylalanine is a fluorinated and methoxylated derivative of the amino acid phenylalanine, serving as a sophisticated chiral building block in advanced organic synthesis. This compound is valued for its role in modulating the physicochemical and metabolic properties of target molecules, particularly in pharmaceutical research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the development of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, especially in protease inhibitor and kinase inhibitor programs.
• Peptidomimetics: Used to incorporate fluorinated, non-natural amino acid residues into peptide analogs to enhance metabolic stability, bioavailability, and binding affinity.
• Agrochemical Synthesis: Serves as a building block for developing novel herbicides, fungicides, and plant growth regulators with improved efficacy and environmental profiles.
• Chemical Biology Probes: Employed in the synthesis of labeled compounds and molecular probes for studying enzyme mechanisms and biological pathways.
• Material Science Research: Potential precursor for specialty polymers and advanced materials where fluorine incorporation can alter surface properties and stability.

Basic Information

Item	Details
Product Name	2,6-Difluoro-3-Methoxy-Dl-Phenylalanine
CAS No.	1256482-66-2
Molecular Formula	C10H11F2NO3
Molecular Weight	231.20 g/mol
Synonyms	DL-2,6-Difluoro-3-methoxyphenylalanine; 3-Methoxy-2,6-difluoro-DL-phenylalanine; (RS)-2-Amino-3-(2,6-difluoro-3-methoxyphenyl)propanoic acid; 2,6-Difluoro-3-methoxy-DL-α-phenylalanine; 2,6-Difluoro-3-methoxy-DL-homophenylalanine; (DL)-2,6-Difluoro-3-methoxyphenylalanine; α-Amino-2,6-difluoro-3-methoxyhydrocinnamic acid
EINECS	Contact for details

Quality Control

Our 2,6-Difluoro-3-Methoxy-Dl-Phenylalanine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity, NMR, and MS for structural confirmation, to ensure it meets the stringent requirements for research and development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	DL-mixture (Racemic)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.