Description

3-(4-Chlorophenoxymethyl)Phenylboronic Acid is a specialized boronic acid derivative that serves as a crucial building block in modern synthetic chemistry. Its value lies in its role as a key intermediate for constructing complex molecules via cross-coupling reactions, enabling the development of advanced materials and active pharmaceutical ingredients. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries who require reliable and consistent synthetic intermediates for their R&D and production processes.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the chlorophenoxymethyl moiety contributes to biological activity.
• Material Science Research: Employed in the creation of organic electronic materials, such as polymers for OLEDs and organic photovoltaics.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing sophisticated ligands used in homogeneous catalysis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: A critical raw material for CROs and CDMOs offering bespoke chemical synthesis services.

Basic Information

Product Name	3-(4-Chlorophenoxymethyl)Phenylboronic Acid
CAS No.	1256358-70-9
Molecular Formula	C13H12BClO3
Molecular Weight	262.49 g/mol
Synonyms	[3-(4-Chlorophenoxymethyl)phenyl]boronic acid; (3-((4-Chlorophenoxy)methyl)phenyl)boronic acid; 3-((4-Chlorophenoxy)methyl)benzeneboronic acid; B-[3-[(4-Chlorophenoxy)methyl]phenyl]boronic acid; 1256358-70-9; 3-(4-Chloro-phenoxymethyl)-phenylboronic acid
EINECS	Contact for details

Quality Control

Our 3-(4-Chlorophenoxymethyl)Phenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for sensitive cross-coupling applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.