Description

4-(4-Cyanophenylmethoxy)Phenylboronic Acid is a specialized boronic acid derivative featuring a cyanophenylmethoxy linker, making it a valuable bifunctional building block in modern synthetic chemistry. This compound is essential for facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology for constructing complex biaryl structures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing biphenyl or heterobiaryl motifs.
• Agrochemical Synthesis: Used in creating novel herbicides, fungicides, and insecticides through palladium-catalyzed cross-coupling.
• Material Science: Serves as a monomer or cross-linking agent in the development of organic electronic materials, such as polymers for OLEDs or OFETs.
• Ligand & Catalyst Development: Employed in the preparation of sophisticated ligands for catalysis or as a building block for metal-organic frameworks (MOFs).
• Chemical Biology & Proteomics: Can be utilized in the synthesis of molecular probes and affinity tags for studying protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical reagent for custom synthesis houses serving the life sciences industry.

Basic Information

Product Name	4-(4-Cyanophenylmethoxy)Phenylboronic Acid
CAS No.	1256355-70-0
Molecular Formula	C14H12BNO3
Molecular Weight	253.07 g/mol
Synonyms	[4-(4-Cyanobenzyloxy)phenyl]boronic acid; 4-(4-Cyanobenzyloxy)benzeneboronic acid; (4-((4-Cyanobenzyl)oxy)phenyl)boronic acid; 4-Cyanobenzyl 4-boronobenzoate (tautomeric form); B-[4-[(4-Cyanophenyl)methoxy]phenyl]boronic acid; 4-(4-Cyanobenzyloxy)phenylboronic Acid; PINACOL ESTER OF 4-(4-CYANOBENZYLOXY)PHENYLBORONIC ACID (common derivative).
EINECS	Contact for details

Quality Control

Our 4-(4-Cyanophenylmethoxy)Phenylboronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and compliance with customer specifications. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent degradation. For long-term storage, consider using a desiccator or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.