Description

2,4-Bis(Methoxycarbonyl)Phenylboronic Acid is a specialized boronic acid derivative featuring dual ester functionalities on the aromatic ring. This compound is a high-value synthetic intermediate prized for its role in facilitating Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern organic synthesis. It is essential for researchers and manufacturers in the pharmaceutical and advanced materials sectors who require precise, modular construction of complex biaryl and heterobiaryl structures for active pharmaceutical ingredients (APIs) and functional organic molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in constructing complex biaryl cores prevalent in kinase inhibitors and other therapeutic agents.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science Research: Employed in the creation of organic electronic materials, such as polymers and small molecules for OLEDs and organic photovoltaics (OPVs).
• Ligand and Catalyst Development: Serves as a precursor for synthesizing sophisticated ligands and organometallic catalysts used in asymmetric synthesis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target engagement.
• Custom Synthesis and Contract Manufacturing: A critical reagent for custom chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Item	Detail
Product Name	2,4-Bis(Methoxycarbonyl)Phenylboronic Acid
CAS No.	1256354-98-9
Molecular Formula	C11H13BO6
Molecular Weight	252.03 g/mol
Synonyms	2,4-Bis(methoxycarbonyl)benzeneboronic acid; (2,4-Dicarbomethoxyphenyl)boronic acid; Dimethyl 5-boronophthalate; 2,4-Di(methoxycarbonyl)phenylboronic acid; 5-Boronoisophthalic acid dimethyl ester; CAS 1256354-98-9
EINECS	Contact for details

Quality Control

Every batch of our 2,4-Bis(Methoxycarbonyl)Phenylboronic Acid is manufactured and tested under a strict quality management system. We guarantee high chemical purity and lot-to-lot consistency critical for sensitive cross-coupling reactions. Certificates of Analysis (COA) detailing identity, purity (typically by HPLC/NMR), and impurity profiles are provided with each shipment to ensure compliance with your research and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%
NMR Purity	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.