Description

Ethyl 1-Chloroisoquinoline-3-Carboxylate is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. This compound is critical for researchers and manufacturers developing novel active pharmaceutical ingredients (APIs) and agrochemicals due to its reactive chloroisoquinoline core. It is primarily utilized by pharmaceutical R&D laboratories, agrochemical companies, and fine chemical producers engaged in the synthesis of complex molecules for drug discovery and crop protection.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential therapeutic agents, including kinase inhibitors and other biologically active isoquinoline derivatives.
• Agrochemical Research: Serves as a crucial building block for developing new-generation herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Used in the research and development of organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components for organic light-emitting diodes (OLEDs).
• Chemical Synthesis: A versatile reagent for constructing complex heterocyclic systems through cross-coupling reactions, nucleophilic substitutions, and cyclization processes.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for methodological studies and the discovery of new chemical entities.

Basic Information

Product Name	Ethyl 1-Chloroisoquinoline-3-Carboxylate
CAS No.	1256353-08-8
Molecular Formula	C₁₂H₁₀ClNO₂
Molecular Weight	235.67 g/mol
Synonyms	1-Chloroisoquinoline-3-carboxylic acid ethyl ester; Ethyl 1-chloro-3-isoquinolinecarboxylate; 3-Carbethoxy-1-chloroisoquinoline; 1-Chloro-3-(ethoxycarbonyl)isoquinoline; Ethyl 1-chloroisoquinoline-3-carboxylate; 1-Chloro-isoquinoline-3-carboxylic acid ethyl ester; Isoquinoline-3-carboxylic acid, 1-chloro-, ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 1-Chloroisoquinoline-3-Carboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting batch-specific results for identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.