Description

5-Acetyl-4-Bromothiophen-2-Boronic Acid is a high-value, multi-functional boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its core value lies in enabling precise carbon-carbon bond formation via Suzuki-Miyaura cross-coupling reactions, a cornerstone technology for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity intermediates for drug discovery, catalyst development, and the synthesis of novel organic electronic materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates containing thiophene and biaryl motifs.
• Agrochemical Synthesis: Used to create novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science: Building block for organic semiconductors, conductive polymers, and liquid crystals used in OLEDs and electronic devices.
• Chemical Research & Development: Versatile reagent for constructing complex heterocyclic compounds and exploring new synthetic pathways in academic and industrial labs.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands used in homogeneous catalysis.
• Custom Synthesis: Foundation for the contract manufacturing of bespoke fine chemicals and advanced intermediates.

Basic Information

Product Name	5-Acetyl-4-Bromothiophen-2-Boronic Acid
CAS No.	1256346-41-4
Molecular Formula	C6H6BBrO3S
Molecular Weight	248.89 g/mol
Synonyms	(5-Acetyl-4-bromothiophen-2-yl)boronic acid; 2-Borono-5-acetyl-4-bromothiophene; 4-Bromo-5-acetylthiophene-2-boronic acid; 5-Acetyl-4-bromo-2-thienylboronic acid; 4-Bromo-5-acetyl-2-thienylboronic acid; 2-Thiopheneboronic acid, 5-acetyl-4-bromo-; AKOS BRN-0792
EINECS	Contact for details

Quality Control

Every batch of 5-Acetyl-4-Bromothiophen-2-Boronic Acid is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure it meets the high standards required for advanced synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality commitment ensures batch-to-batch consistency and reliability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical 97-99%)
Water Content (KF)	≤ 1.0%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.