Description

(Pyridin-2-Ylthio)Methylboronic Acid is a specialized organoboron compound featuring a pyridylthio moiety, serving as a valuable bifunctional building block in advanced synthetic chemistry. Its core value lies in its dual reactivity, where the boronic acid group enables Suzuki-Miyaura cross-coupling reactions, while the heterocyclic sulfur unit can act as a ligand or participate in further functionalization. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecular architectures, particularly in drug discovery and material science applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing heterocyclic scaffolds for kinase inhibitors or other targeted therapies.
• Suzuki-Miyaura Cross-Coupling: Utilized as a versatile boronic acid coupling partner for the formation of carbon-carbon bonds with aryl or vinyl halides, a cornerstone reaction in medicinal chemistry.
• Ligand Synthesis: The pyridylthio group can be employed to develop novel ligands for catalysis or metal-organic frameworks (MOFs).
• Agrochemical Research: Used in the design and synthesis of novel crop protection agents and herbicides.
• Material Science: Serves as a monomer or functional additive in the development of advanced polymers and electronic materials.
• Chemical Biology Probes: Acts as a building block for creating molecular probes to study biological processes and enzyme functions.

Basic Information

Item	Details
Product Name	(Pyridin-2-Ylthio)Methylboronic Acid
CAS No.	1256346-00-5
Molecular Formula	C7H8BNO2S
Molecular Weight	181.02 g/mol
Synonyms	2-((Methylboronic acid)thio)pyridine; (2-Pyridylthio)methylboronic Acid; Pyridine-2-thiomethylboronic Acid; B-(Pyridin-2-Ylthiomethyl)boronic Acid; 2-Pyridinylthiomethylboronic Acid; (Pyridin-2-ylsulfanyl)methylboronic Acid; (2-Pyridinylthio)methylboronic Acid
EINECS	Contact for details

Quality Control

Our (Pyridin-2-Ylthio)Methylboronic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.