Description

4-Acetyl-3-Nitrophenylboronic Acid is a specialized boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its molecular structure, featuring both an acetyl and a nitro group ortho to the boronic acid functionality, makes it a valuable reagent for constructing complex molecules via cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries engaged in developing new active ingredients. Its precise reactivity profile enables the synthesis of novel compounds with potential biological activity.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting complex diseases.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a versatile boronic acid coupling partner for forming carbon-carbon bonds with aryl or vinyl halides, a cornerstone of medicinal chemistry.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides by constructing specific aromatic frameworks.
• Material Science & OLED Development: Employed in the synthesis of organic electronic materials and emissive layers for display technologies.
• Ligand Synthesis for Catalysis: Acts as a starting material for creating sophisticated ligands used in asymmetric catalysis and transition metal complexes.
• Chemical Biology & Probe Development: Utilized in designing molecular probes and sensors for studying biological processes and enzyme activity.

Basic Information

Product Name	4-Acetyl-3-Nitrophenylboronic Acid
CAS No.	1256345-63-7
Molecular Formula	C8H8BNO5
Molecular Weight	209.97 g/mol
Synonyms	(4-Acetyl-3-nitrophenyl)boronic acid; 3-Nitro-4-acetylbenzeneboronic acid; 4-Acetyl-3-nitrobenzeneboronic acid; Boronic acid, B-(4-acetyl-3-nitrophenyl)-; 4-Acetyl-3-nitro-phenylboronic acid; 4-Acetyl-3-nitrophenyl-B(OH)2
EINECS	Contact for details

Quality Control

Our 4-Acetyl-3-Nitrophenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and process development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment. We adhere to relevant industry standards, and specifications can be tailored to support your specific project needs from laboratory to pilot scale.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed and under an inert atmosphere for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.