Description

2-Amino-5-Carboxy-4-Chloro-1,3-Thiazole is a heterocyclic organic compound featuring a thiazole core functionalized with amino, carboxy, and chloro groups, making it a versatile and valuable building block in advanced chemical synthesis. Its unique structure provides a critical scaffold for the development of novel active pharmaceutical ingredients (APIs) and specialty agrochemicals. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to create new molecules with targeted biological activity.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in therapeutic areas requiring complex heterocyclic architectures.
• Agrochemical Synthesis: Serves as a crucial precursor in the manufacture of advanced herbicides, fungicides, and insecticides, leveraging its reactive sites for structural diversification.
• Fine Chemical Production: Used in the synthesis of complex dyes, pigments, and other specialty chemicals where the thiazole moiety imparts specific properties.
• Research & Development: An important reagent in academic and industrial R&D labs for exploring new chemical entities and reaction pathways in medicinal and synthetic chemistry.
• Material Science: Potential application as a monomer or functional additive in the development of advanced polymers and functional materials.

Basic Information

Item	Details
Product Name	2-Amino-5-Carboxy-4-Chloro-1,3-Thiazole
CAS No.	1255772-87-2
Molecular Formula	C4H3ClN2O2S
Molecular Weight	178.60 g/mol
Synonyms	4-Chloro-1,3-thiazole-2,5-dicarboxylic acid, 2-amino-; 2-Amino-4-chloro-1,3-thiazole-5-carboxylic acid; 4-Chloro-2-amino-1,3-thiazole-5-carboxylic acid; 5-Carboxy-4-chloro-2-aminothiazole; ACCAT; 2-Amino-4-chlorothiazole-5-carboxylic acid; 4-Chloro-2-aminothiazole-5-carboxylic acid
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-5-Carboxy-4-Chloro-1,3-Thiazole is produced and tested under a strict quality management system to ensure consistency and reliability for your critical syntheses. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring the material meets the stringent requirements of pharmaceutical and advanced chemical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.