Description

(R)-4-(3-((tert-Butoxycarbonyl)Amino)-1-(Isoquinolin-6-Ylamino)-1-Oxopropan-2-Yl)Benzyl 2,4-Dimethylbenzoate is a sophisticated chiral organic compound designed for advanced pharmaceutical research and development. This molecule serves as a critical building block or intermediate in the synthesis of complex active pharmaceutical ingredients (APIs), particularly those targeting specific biological pathways. It is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require high-purity, structurally defined intermediates for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of novel therapeutic agents, especially in oncology and central nervous system (CNS) drug candidates.
• Protease Inhibitor Research: Potential building block for the development of inhibitors targeting specific proteases, given the presence of the Boc-protected amino and isoquinoline moieties.
• Peptidomimetic Chemistry: Used in the design and synthesis of peptidomimetics, where the compound's structure can mimic natural peptide substrates.
• Chemical Biology Probes: Serves as a precursor for creating labeled or tagged molecular probes to study enzyme function and protein-protein interactions.
• Process Chemistry & Scale-Up: Employed in route scouting and optimization for the commercial-scale production of target APIs.
• Asymmetric Synthesis: Utilized in reactions requiring high enantiomeric purity due to its defined (R)-configuration.

Basic Information

Product Name	(R)-4-(3-((tert-Butoxycarbonyl)Amino)-1-(Isoquinolin-6-Ylamino)-1-Oxopropan-2-Yl)Benzyl 2,4-Dimethylbenzoate
CAS No.	1253955-20-2
Molecular Formula	C33H36N4O5
Molecular Weight	568.67 g/mol
Synonyms	(R)-4-(3-((tert-Butoxycarbonyl)amino)-1-(isoquinolin-6-ylamino)-1-oxopropan-2-yl)benzyl 2,4-dimethylbenzoate; 2,4-Dimethylbenzoic Acid 4-[[(2R)-3-[[(1,1-Dimethylethoxy)carbonyl]amino]-2-[(6-isoquinolinylamino)carbonyl]propyl]phenyl]methyl Ester; Boc-D-2,6-Diisopropylphenylalanine; (R)-Boc-Phe(2,4-diMe)-OH Isoquinolin-6-ylamide; A potential intermediate for kinase inhibitors. Contact for a complete synonym list.
EINECS	Contact for details

Quality Control

Our (R)-4-(3-((tert-Butoxycarbonyl)Amino)-1-(Isoquinolin-6-Ylamino)-1-Oxopropan-2-Yl)Benzyl 2,4-Dimethylbenzoate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing purity (typically by HPLC), chiral purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. Under these conditions, the product is stable for at least two years from the date of receipt. Allow the sealed container to equilibrate to room temperature before opening to minimize moisture condensation. The compound should be considered moisture-sensitive.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.