Description

1-(4-Bromo-3-Indolyl)-2,2,2-Trifluoroethanone is a specialized trifluoromethyl ketone derivative of indole, serving as a high-value synthetic intermediate in advanced organic chemistry. This compound matters for its role in constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for synthesizing novel active compounds and functional materials.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the biological activity of the indole and trifluoromethyl motifs.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of advanced organic electronic materials and specialty polymers.
• Chemical Biology Probe Development: Utilized in the design and synthesis of activity-based probes and inhibitors for enzyme studies.
• Academic & Institutional Research: Employed in universities and research institutes for methodological development in heterocyclic and fluoroorganic chemistry.
• Scale-up Process Chemistry: Investigated for use in optimizing synthetic routes from laboratory to pilot-plant scale for commercial production.

Basic Information

Product Name	1-(4-Bromo-3-Indolyl)-2,2,2-Trifluoroethanone
CAS No.	1253929-39-3
Molecular Formula	C10H5BrF3NO
Molecular Weight	292.05 g/mol
Synonyms	4-Bromo-1-(2,2,2-trifluoroacetyl)-1H-indole; 4-Bromo-3-(2,2,2-trifluoroacetyl)indole; 1H-Indole-3-ethanone, 4-bromo-α,α,α-trifluoro-; 4-Bromo-α,α,α-trifluoro-1H-indole-3-acetone; 4-Bromo-3-indolyl trifluoromethyl ketone; 4-Bromo-1H-indol-3-yl trifluoromethyl ketone; 4-Bromo-3-(trifluoroacetyl)indole
EINECS	Contact for details

Quality Control

Our 1-(4-Bromo-3-Indolyl)-2,2,2-Trifluoroethanone undergoes rigorous quality testing to ensure compliance with industry standards for research and development. We provide comprehensive analytical data including HPLC purity, NMR, and mass spectrometry for identity confirmation. Certificates of Analysis (COA) are available upon request for every batch, detailing all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.