Description

4-Fluoro-1H-Indazol-6-Ol is a high-purity fluorinated indazole derivative, a crucial building block in modern organic synthesis. Its value lies in its unique molecular scaffold, which is essential for constructing complex molecules with targeted biological activity. This compound is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing new active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, especially kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the synthesis of advanced crop protection agents and pesticides due to the bioactivity of the indazole core.
• Material Science: Serves as a precursor for specialty chemicals and advanced organic materials, including liquid crystals and organic light-emitting diodes (OLEDs).
• Biochemical Tool Compound: Employed in life science research as a probe or reference standard for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: A fundamental starting material for custom synthesis projects and scale-up production under cGMP conditions for clinical trials.

Basic Information

Product Name	4-Fluoro-1H-Indazol-6-Ol
CAS No.	1253791-66-0
Molecular Formula	C7H5FN2O
Molecular Weight	152.13 g/mol
Synonyms	6-Hydroxy-4-fluoro-1H-indazole; 4-Fluoro-6-hydroxy-1H-indazole; 4-Fluoro-1H-indazol-6-ol; 1H-Indazol-6-ol, 4-fluoro-; 1253791-66-0; 4-Fluoroindazol-6-ol; 6-Hydroxy-4-fluoroindazole
EINECS	Contact for details

Quality Control

Our 4-Fluoro-1H-Indazol-6-Ol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment supports applications requiring high-purity intermediates for research and cGMP-compliant production.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its property of being easily oxidized, long-term storage under an inert atmosphere (e.g., nitrogen or argon) is recommended for optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.