Description

2-Bromo-5-(Cyclopropylmethylsulfonyl)Thiophene is a high-purity, advanced pharmaceutical intermediate characterized by its unique thiophene core functionalized with bromo and cyclopropylmethylsulfonyl groups. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with targeted therapeutic effects. It is primarily needed by R&D scientists and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries for developing new drug candidates and high-value fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly in kinase inhibitor and antiviral research.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging its heterocyclic structure for biological activity.
• Material Science: Acts as a monomer or functional additive in the creation of conductive polymers and advanced organic electronic materials.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Stille) and nucleophilic substitutions to construct complex molecular architectures.
• Chemical Biology Probe Development: Utilized in creating molecular tools for studying enzyme function and cellular pathways.

Basic Information

Product Name	2-Bromo-5-(Cyclopropylmethylsulfonyl)Thiophene
CAS No.	1253791-36-4
Molecular Formula	C8H9BrO2S2
Molecular Weight	281.19 g/mol
Synonyms	2-Bromo-5-(cyclopropylmethylsulfonyl)thiophene; Thiophene, 2-bromo-5-[(cyclopropylmethyl)sulfonyl]-; 2-Bromo-5-[(cyclopropylmethyl)sulfonyl]thiophene; 2-Bromo-5-(cyclopropylmethylsulfonyl)thiophene; 1253791-36-4; 2-Bromo-5-(cyclopropylmethylsulfonyl)thiophene; 2-Br-5-CPMS-Thiophene
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-(Cyclopropylmethylsulfonyl)Thiophene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing results from HPLC, NMR, and GC-MS analysis. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.