Description

1-(5-Bromo-1H-Indol-7-Yl)Ethanone CAS NO 1253789-74-0 is a high-purity brominated indole derivative, a crucial advanced intermediate in modern organic synthesis. Its value lies in providing a versatile and reactive scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly in oncology and CNS (Central Nervous System) therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides that leverage the indole core's biological activity.
• Chemical Biology Probe Synthesis: Serves as a precursor for creating molecular probes to study biological pathways and protein functions.
• Material Science Research: A potential monomer or precursor for synthesizing specialized organic electronic materials and dyes.
• Academic & Contract Research: Employed in university and CRO (Contract Research Organization) laboratories for method development and novel compound library synthesis.

Basic Information

Product Name	1-(5-Bromo-1H-Indol-7-Yl)Ethanone
CAS No.	1253789-74-0
Molecular Formula	C10H8BrNO
Molecular Weight	238.08 g/mol
Synonyms	5-Bromo-7-acetylindole; 7-Acetyl-5-bromo-1H-indole; 1-(5-Bromo-1H-indol-7-yl)ethan-1-one; Ethanone, 1-(5-bromo-1H-indol-7-yl)-; 5-Bromo-7-acetyl-1H-indole; 1-(5-Bromo-7-indolyl)ethanone
EINECS	Contact for details

Quality Control

Our 1-(5-Bromo-1H-Indol-7-Yl)Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to cGMP (current Good Manufacturing Practice) standards ensures reliability for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is light-sensitive (store away from light) and should be handled under an inert atmosphere for long-term storage to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.