Description

2-Cyano-4-Methyl-Thiazole-5-Carboxylic Acid Ethyl Ester is a high-value, multi-functional heterocyclic building block essential for advanced organic synthesis. Its core value lies in its versatile molecular scaffold, which is designed for the efficient construction of complex pharmacophores and agrochemical intermediates. This compound is critically needed by research and development chemists in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the thiazole ring's bioactivity.
• Material Science Research: Serves as a monomer or functional additive in the development of specialty polymers and advanced organic electronic materials.
• Chemical Biology & Proteomics: Employed as a versatile scaffold for designing activity-based probes and molecular tags to study biological systems.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	2-Cyano-4-Methyl-Thiazole-5-Carboxylic Acid Ethyl Ester
CAS No.	1253654-53-3
Molecular Formula	C9H8N2O2S
Molecular Weight	208.24 g/mol
Synonyms	Ethyl 2-Cyano-4-methyl-1,3-thiazole-5-carboxylate; 4-Methyl-2-cyano-thiazole-5-carboxylic acid ethyl ester; 5-Carbethoxy-4-methyl-2-cyanothiazole; 2-Cyano-4-methylthiazole-5-carboxylic acid ethyl ester; 5-(Ethoxycarbonyl)-4-methyl-2-cyanothiazole; 4-Methyl-2-cyanothiazole-5-carboxylic acid ethyl ester; Ethyl 4-methyl-2-cyanothiazole-5-carboxylate
EINECS	Contact for details

Quality Control

Every batch of 2-Cyano-4-Methyl-Thiazole-5-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our standard grade meets high-purity requirements suitable for research and commercial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles by HPLC, NMR, and MS is provided with each shipment to guarantee supply reliability and technical compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.