Description

2-Chloro-N,n-Dimethyl-Ethan Amine-D4 Hydrochloride is a deuterated analog of a key pharmaceutical intermediate, offering a stable isotopic label for advanced research and development. This compound is critical for metabolic and pharmacokinetic studies, providing enhanced analytical precision in mass spectrometry. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and manufacturers of active pharmaceutical ingredients (APIs) requiring deuterium-labeled building blocks.

Application

• Pharmaceutical Intermediate: Serves as a deuterated building block in the synthesis of novel drug candidates, particularly for metabolic pathway tracing.
• Metabolic Studies: Used as an internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) for accurate quantification of metabolites.
• Pharmacokinetic Research: Enables precise tracking of drug absorption, distribution, metabolism, and excretion (ADME) in preclinical and clinical studies.
• Isotope Labeling: Provides a stable deuterium label for mechanistic studies in organic chemistry and biochemistry.
• Reference Standard: Acts as a certified reference material (CRM) for quality control and method validation in analytical laboratories.

Basic Information

Product Name	2-Chloro-N,n-Dimethyl-Ethan Amine-D4 Hydrochloride
CAS No.	1252995-12-2
Molecular Formula	C4H5D4Cl2N
Molecular Weight	154.05 g/mol
Synonyms	2-Chloro-N,N-dimethylethanamine-d4 hydrochloride; (2-Chloroethyl)dimethylamine-d4 hydrochloride; N,N-Dimethyl-2-chloroethylamine-d4 hydrochloride; Dimethylaminoethyl chloride-d4 hydrochloride; DMAE-Cl-d4 HCl; Deutero-Dimethylaminoethyl Chloride Hydrochloride; 2-(Dimethylamino)ethyl chloride-d4 hydrochloride; N,N-Dimethyl-2-chloroethanaminium-d4 chloride
EINECS	Contact for details

Quality Control

Our deuterated compounds are produced under strict quality control protocols to ensure high isotopic purity and chemical integrity, essential for sensitive analytical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing assay, isotopic enrichment (D-content), and impurity profiles via NMR and HPLC/MS. We adhere to cGMP guidelines where applicable to support regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.