Description

2-(2-Chloroethyl-D4)- CAS NO 1252995-10-0 is a deuterium-labeled isotopologue of 2-chloroethanol, a valuable building block for chemical synthesis. This compound is essential for research and development in pharmaceutical and agrochemical fields, where deuterium labeling is used to study metabolic pathways, reaction mechanisms, and to improve the pharmacokinetic profiles of active ingredients. It is primarily utilized by medicinal chemists, process development scientists, and analytical laboratories requiring high-purity, stable isotope-labeled intermediates.

Application

• Pharmaceutical Research: As a deuterated synthon for the preparation of isotopically labeled drug candidates and metabolites for pharmacokinetic (PK) and absorption, distribution, metabolism, and excretion (ADME) studies.
• Analytical Chemistry: Serving as an internal standard in quantitative mass spectrometry (MS) and liquid chromatography-mass spectrometry (LC-MS) methods, enhancing accuracy and reliability in bioanalysis.
• Mechanistic Studies: A tool for investigating chemical and enzymatic reaction mechanisms through kinetic isotope effect (KIE) experiments.
• Agrochemical Development: Used in the synthesis of deuterated analogs of pesticides and herbicides to study environmental fate and degradation pathways.
• Material Science: Potential precursor for synthesizing specialty polymers and materials where deuterium incorporation modifies physical properties.

Basic Information

Product Name	2-(2-Chloroethyl-D4)- CAS NO 1252995-10-0
CAS No.	1252995-10-0
Molecular Formula	C2D4H2ClO
Molecular Weight	85.53 g/mol
Synonyms	2-Chloroethanol-d4; Ethanol-d4, 2-chloro-; 2-Chloro-1,1,2,2-tetradeuteroethanol; Deuterated 2-Chloroethanol; [1,1,2,2-2H4]-2-Chloroethanol; 2-Chloroethyl-d4 Alcohol; 2-Hydroxyethyl-d4 Chloride; NSC 8813-d4
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for stable isotope-labeled compounds. Each batch is characterized to confirm isotopic purity (D-enrichment) and chemical purity. Certificates of Analysis (COA) are provided, detailing results from NMR (1H, 13C), mass spectrometry, and chromatographic purity assays (GC or HPLC). We adhere to cGMP principles for manufacturing controls where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.