Description

2-(6-(Trifluoromethoxy)-1H-Indol-3-Yl)Ethanamine Hydrochloride is a high-purity, pharmaceutically relevant indole derivative. This compound is a critical building block in medicinal chemistry, valued for its role in the synthesis of novel bioactive molecules. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of central nervous system (CNS) and other therapeutic agents.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates targeting serotonin and other neurotransmitter receptors.
• Medicinal Chemistry Research: A versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Used in pharmacological assays to study receptor binding and functional activity.
• Academic Research: Employed in universities and research institutes for studying indole chemistry and developing new synthetic methodologies.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.

Basic Information

Product Name	2-(6-(Trifluoromethoxy)-1H-Indol-3-Yl)Ethanamine Hydrochloride
CAS No.	1252686-45-5
Molecular Formula	C11H12F3N2O • HCl
Molecular Weight	280.69 g/mol (Free base: 244.22 g/mol)
Synonyms	6-(Trifluoromethoxy)tryptamine hydrochloride; 2-(6-(Trifluoromethoxy)-1H-indol-3-yl)ethan-1-amine hydrochloride; 5-(Trifluoromethoxy)tryptamine hydrochloride (common numbering); 6-TFMT HCl; 2-(6-Trifluoromethoxy-1H-indol-3-yl)ethylamine hydrochloride; α-Methyl-6-(trifluoromethoxy)serotonin precursor; 6-Trifluoromethoxytryptamine HCl
EINECS	Contact for details

Quality Control

Our 2-(6-(Trifluoromethoxy)-1H-Indol-3-Yl)Ethanamine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance with research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.