Description

4-Bromo-1-(4-Methoxyphenyl)-5-Methylpyrazole is a high-purity, functionalized pyrazole derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a versatile intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its specific bromine and methoxyphenyl substituents enable precise molecular modifications. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex heterocyclic frameworks.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its pyrazole core.
• Material Science: Building block for creating functional organic materials, such as ligands for catalysts or components in organic electronics.
• Chemical Synthesis: Versatile reagent for cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and further functionalization due to the reactive bromine atom.
• Academic & Industrial R&D: Serves as a standard or novel scaffold for methodological studies and library synthesis in medicinal chemistry.

Basic Information

Product Name	4-Bromo-1-(4-Methoxyphenyl)-5-Methylpyrazole
CAS No.	1252572-62-5
Molecular Formula	C11H11BrN2O
Molecular Weight	267.12 g/mol
Synonyms	4-Bromo-1-(4-methoxyphenyl)-5-methyl-1H-pyrazole; 1-(4-Methoxyphenyl)-4-bromo-5-methylpyrazole; 4-Bromo-5-methyl-1-(4-methoxyphenyl)-1H-pyrazole; 1H-Pyrazole, 4-bromo-1-(4-methoxyphenyl)-5-methyl-; 1252572-62-5; 4-Bromo-1-(p-methoxyphenyl)-5-methylpyrazole
EINECS	Contact for details

Quality Control

Our 4-Bromo-1-(4-Methoxyphenyl)-5-Methylpyrazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber or opaque.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.