Description

Sodium 4-Hydroxybutyrate-D4 is a stable isotope-labeled analog of sodium 4-hydroxybutyrate, where four hydrogen atoms are replaced by deuterium. This high-purity compound is essential for use as an internal standard in quantitative analytical methods, ensuring unparalleled accuracy and reliability in research and quality control. It is a critical material for scientists and quality assurance professionals in the pharmaceutical, forensic, and clinical research industries who require definitive results in mass spectrometry and NMR studies.

Application

• Internal Standard for Mass Spectrometry (MS): Provides precise quantification of sodium 4-hydroxybutyrate (GHB) in complex biological matrices such as plasma, urine, and tissue samples.
• Metabolic Pathway Tracing: Used in pharmacokinetic and metabolic studies to track the absorption, distribution, metabolism, and excretion (ADME) of GHB.
• Forensic Analysis and Toxicology: Enables accurate and legally defensible measurement of GHB levels in forensic investigations and doping control.
• Pharmaceutical Research & Development: Supports method development and validation for drug substance and product analysis in compliance with GLP and GMP guidelines.
• Nuclear Magnetic Resonance (NMR) Spectroscopy: Serves as a deuterated reference compound to elucidate molecular structure and dynamics.
• Quality Control and Assurance: Acts as a critical reference material for in-house method validation and ensuring batch-to-batch consistency in analytical laboratories.

Basic Information

Product Name	Sodium 4-Hydroxybutyrate-D4
CAS No.	1251763-08-2
Molecular Formula	C4H3D4NaO3
Molecular Weight	130.12 g/mol (approx.)
Synonyms	Sodium 4-Hydroxy[2,3,3,4-2H4]butyrate; Sodium GHB-D4; Sodium Oxybate-D4; Sodium 4-Hydroxybutanoate-D4; Deuterated Sodium γ-Hydroxybutyrate; [2,3,3,4-2H4]-4-Hydroxybutanoic Acid Sodium Salt; Sodium (2,3,3,4-tetradeuterio-4-hydroxybutanoate)
EINECS	Contact for details

Quality Control

Our Sodium 4-Hydroxybutyrate-D4 is manufactured under strict quality systems to ensure the high chemical and isotopic purity required for analytical applications. Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing parameters such as isotopic purity (D-enrichment), chemical purity (HPLC), and identification (NMR, MS). We adhere to relevant industry standards for reference materials to guarantee reliable and reproducible performance in your critical assays.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.