Description

(1-Acetyl-1,2,3,6-Tetrahydropyridin-4-Yl)Boronic Acid is a high-purity, advanced pharmaceutical intermediate belonging to the class of heterocyclic boronic acids. This compound is a critical building block in modern medicinal chemistry, primarily valued for its role in facilitating the Suzuki-Miyaura cross-coupling reaction, a cornerstone for constructing complex carbon-carbon bonds. It is essential for research and development chemists in the pharmaceutical and agrochemical industries working on novel active ingredients, particularly in the synthesis of drug candidates targeting the central nervous system and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, especially for central nervous system (CNS) targets.
• Suzuki-Miyaura Cross-Coupling Reagent: Enables the efficient formation of carbon-carbon bonds for constructing complex molecular architectures in medicinal chemistry.
• Agrochemical Research: Used in the development of new active ingredients for crop protection and pest management.
• Chemical Biology & Proteomics: Serves as a versatile handle for bioconjugation and the development of chemical probes.
• Material Science Research: Potential precursor for creating novel organic electronic materials and polymers.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.

Basic Information

Product Name	(1-Acetyl-1,2,3,6-Tetrahydropyridin-4-Yl)Boronic Acid
CAS No.	1251537-34-4
Molecular Formula	C7H12BNO3
Molecular Weight	168.99 g/mol
Synonyms	1-(1,2,3,6-Tetrahydro-4-pyridinyl)ethanone-4-boronic Acid; 4-Borono-1-acetyl-1,2,3,6-tetrahydropyridine; 1-Acetyl-1,2,3,6-tetrahydropyridine-4-boronic Acid; 1-Acetyl-4-borono-1,2,3,6-tetrahydropyridine; 1-Acetyl-1,2,3,6-tetrahydro-4-pyridineboronic Acid; (1-Acetyl-1,2,3,6-tetrahydro-4-pyridinyl)boronic Acid
EINECS	Contact for details

Quality Control

Our (1-Acetyl-1,2,3,6-Tetrahydropyridin-4-Yl)Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and consistent performance for sensitive cross-coupling applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to maintain optimal stability and reactivity.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.