Description

2-(3-Hydroxy-Piperidin-1-Yl)-1-Thiophen-2-Yl-Ethanone is a high-purity, advanced pharmaceutical intermediate characterized by its piperidine and thiophene heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is primarily required by pharmaceutical R&D laboratories, contract research and manufacturing organizations (CROs/CMOs), and fine chemical producers engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• CNS Drug Development: Used in the research and synthesis of potential therapeutics for neurological and psychiatric disorders.
• Oncology Research: Employed as a building block for novel small-molecule inhibitors and targeted cancer therapies.
• Contract Manufacturing: Supplied to CMOs for the scale-up and cGMP production of clinical trial materials and commercial APIs.
• Academic Research: Utilized in university and institutional labs for biochemical studies and the development of new synthetic methodologies.

Basic Information

Product Name	2-(3-Hydroxy-Piperidin-1-Yl)-1-Thiophen-2-Yl-Ethanone
CAS No.	1251112-82-9
Molecular Formula	C11H15NO2S
Molecular Weight	225.31 g/mol
Synonyms	1-(2-Thienyl)-2-(3-hydroxy-1-piperidinyl)ethanone; 2-(3-Hydroxypiperidin-1-yl)-1-(thiophen-2-yl)ethan-1-one; 2-(3-Hydroxy-1-piperidinyl)-1-(2-thienyl)ethanone; Ethanone, 1-(2-thienyl)-2-(3-hydroxy-1-piperidinyl)-; 2-(3-Hydroxy-piperidin-1-yl)-1-thiophen-2-yl-ethanone
EINECS	Contact for details

Quality Control

Our 2-(3-Hydroxy-Piperidin-1-Yl)-1-Thiophen-2-Yl-Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and cGMP manufacturing. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.