Description

3-(Boc-Aminomethyl)Pyrazole is a high-purity, protected amine building block essential for modern organic synthesis. This compound matters because it provides a versatile and stable intermediate for constructing complex molecules, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications such as peptide mimetics and heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing pyrazole and amine functionalities.
• Peptidomimetics & PROTACs: Used to introduce protected amine handles into peptide backbones or linker systems for Proteolysis Targeting Chimeras (PROTACs) and other bifunctional molecules.
• Agrochemical Synthesis: Serves as a precursor in the development of novel herbicides, fungicides, and insecticides that utilize heterocyclic scaffolds.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tool compounds for target identification and validation in biological systems.
• Material Science: Can be utilized as a monomer or functionalizing agent in the creation of specialty polymers and advanced materials with tailored properties.
• Custom Synthesis & Contract Research: A valuable starting material for custom synthesis houses and CROs (Contract Research Organizations) serving the global life sciences sector.

Basic Information

Product Name	3-(Boc-Aminomethyl)Pyrazole
CAS No.	1251033-82-5
Molecular Formula	C9H15N3O2
Molecular Weight	197.24 g/mol
Synonyms	1H-Pyrazole-3-methanamine, N-[(1,1-dimethylethoxy)carbonyl]-; tert-Butyl N-[(1H-pyrazol-3-yl)methyl]carbamate; 3-(Boc-aminomethyl)-1H-pyrazole; Boc-AM-Pyrazole; N-Boc-3-(aminomethyl)pyrazole; (1H-Pyrazol-3-ylmethyl)carbamic acid tert-butyl ester; 3-((tert-Butoxycarbonylamino)methyl)-1H-pyrazole; Boc-protected 3-aminomethylpyrazole
EINECS	Contact for details

Quality Control

Our 3-(Boc-Aminomethyl)Pyrazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with full specification data are provided for every shipment, supporting compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C or as indicated on the label. This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere or in a controlled, low-humidity environment to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.