Description

cis-tert-Butyl3,4,4A,5-Tetrahydro-1H-Pyrido[4,3-B]Indole-2(9Bh)-Carboxylate is a high-purity, advanced pharmaceutical intermediate of significant synthetic value. This compound serves as a critical building block in the synthesis of complex heterocyclic molecules, particularly those with potential biological activity. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates, particularly those targeting the central nervous system.
• Organic Synthesis Building Block: Used in research-scale and process chemistry for constructing fused indole and pyridoindole ring systems.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and the discovery of new pharmacophores with potential therapeutic applications.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up of novel chemical entities for clinical trials.
• Academic Research: Utilized in university and institutional labs for methodological development and the study of heterocyclic chemistry.

Basic Information

Product Name	cis-tert-Butyl3,4,4A,5-Tetrahydro-1H-Pyrido[4,3-B]Indole-2(9Bh)-Carboxylate
CAS No.	1251021-98-3
Molecular Formula	C16H20N2O2
Molecular Weight	272.34 g/mol
Synonyms	cis-tert-Butyl 2,3,4,4a-tetrahydro-1H-pyrido[4,3-b]indole-2-carboxylate; tert-Butyl (3aR,9bS)-2,3,3a,4-tetrahydro-1H-pyrido[4,3-b]indole-2-carboxylate; (3aR,9bS)-2-(tert-Butoxycarbonyl)-2,3,3a,4-tetrahydro-1H-pyrido[4,3-b]indole; BOC-protected cis-tetrahydro-β-carboline derivative; cis-2-Boc-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole; (3aR,9bS)-1,2,3,3a,4,9b-Hexahydropyrido[4,3-b]indole-2-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our cis-tert-Butyl3,4,4A,5-Tetrahydro-1H-Pyrido[4,3-B]Indole-2(9Bh)-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert gas purging to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.