Description

tert-Butyl 4-(5-Bromo-1H-Benzo[D]Imidazol-1-Yl)Azepane-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a unique heterocyclic structure. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new therapeutic agents, particularly in oncology and CNS drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting specific enzyme pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Protease Inhibitor Development: The benzimidazole and azepane motifs make it valuable for creating potential protease or kinase inhibitors.
• Chemical Biology Probes: Employed in the development of chemical probes to study biological processes and identify new drug targets.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.
• Academic Research: Used in university and institutional labs for fundamental research in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	tert-Butyl 4-(5-Bromo-1H-Benzo[D]Imidazol-1-Yl)Azepane-1-Carboxylate
CAS No.	1251017-90-9
Molecular Formula	C17H22BrN3O2
Molecular Weight	380.28 g/mol
Synonyms	1-(1-(tert-Butoxycarbonyl)azepan-4-yl)-5-bromo-1H-benzo[d]imidazole; 5-Bromo-1-(1-(tert-butoxycarbonyl)azepan-4-yl)-1H-benzimidazole; tert-Butyl 4-(5-bromo-1H-benzo[d]imidazol-1-yl)azepane-1-carboxylate; 4-(5-Bromo-1H-benzoimidazol-1-yl)-1-(tert-butoxycarbonyl)azepane; BOC-4-(5-Bromo-1H-benzimidazol-1-yl)azepane; Azepane-1-carboxylic acid, 4-(5-bromo-1H-benzimidazol-1-yl)-, 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(5-Bromo-1H-Benzo[D]Imidazol-1-Yl)Azepane-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes to ensure the material meets the stringent requirements of pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.