Description

cis-tert-Butyl 1,3A,4,8B-Tetrahydropyrrolo[3,4-B]Indole-2(3H)-Carboxylate (Wx115073) is a high-purity, advanced pharmaceutical intermediate featuring a complex fused indole-pyrrolidine scaffold. This compound is of significant value in medicinal chemistry for its role as a key building block in the synthesis of novel bioactive molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly those targeting central nervous system (CNS) disorders and other complex disease pathways.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates, especially those with fused heterocyclic structures.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the discovery of new chemical entities (NCEs).
• CNS Drug Development: Used in the research and development of potential therapeutics for neurological and psychiatric conditions, leveraging the indole core's relevance to neuroactive compounds.
• Process Chemistry & Scale-Up: Employed in route scouting, optimization, and pilot-scale production for clinical trial material (CTM) manufacturing.
• Contract Research & Manufacturing (CRAM): Supplied to organizations providing custom synthesis and development services for the global pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	cis-tert-Butyl 1,3A,4,8B-Tetrahydropyrrolo[3,4-B]Indole-2(3H)-Carboxylate (Wx115073)
CAS No.	1251016-05-3
Molecular Formula	C17H22N2O2
Molecular Weight	286.37 g/mol
Synonyms	tert-Butyl cis-1,3a,4,8b-tetrahydropyrrolo[3,4-b]indole-2(3H)-carboxylate; WX-115073; WX115073; 1,3a,4,8b-Tetrahydropyrrolo[3,4-b]indole-2(3H)-carboxylic acid, 1,1-dimethylethyl ester, cis-; cis-1,1-Dimethylethyl 1,3a,4,8b-tetrahydropyrrolo[3,4-b]indole-2(3H)-carboxylate; cis-tert-Butyl octahydropyrrolo[3,4-b]indole-2-carboxylate
EINECS	Contact for details

Quality Control

Our cis-tert-Butyl 1,3A,4,8B-Tetrahydropyrrolo[3,4-B]Indole-2(3H)-Carboxylate (Wx115073) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports compliance with cGMP guidelines for pharmaceutical intermediates, ensuring reliability for your research and development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). For long-term storage, consider keeping the material under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.