Description

Ethyl 6-Bromoindolizine-2-Carboxylate is a high-purity, advanced pharmaceutical intermediate and versatile heterocyclic building block. This compound is critical for the synthesis of complex molecules, particularly in medicinal chemistry and agrochemical research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of indolizine-based drug candidates, including potential kinase inhibitors, anti-cancer agents, and anti-inflammatory compounds.
• Agrochemical Research: Serves as a building block for developing new pesticides and herbicides with novel modes of action.
• Material Science: Used in the research and development of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors, due to the indolizine core's electronic properties.
• Chemical Synthesis: Employed in organic synthesis for constructing complex heterocyclic frameworks through cross-coupling reactions (e.g., Suzuki, Sonogashira) and functional group transformations.
• Academic & Contract Research: Essential for university laboratories and CROs (Contract Research Organizations) conducting exploratory chemistry and method development.

Basic Information

Product Name	Ethyl 6-Bromoindolizine-2-Carboxylate
CAS No.	1251014-35-3
Molecular Formula	C11H10BrNO2
Molecular Weight	268.11 g/mol
Synonyms	6-Bromoindolizine-2-carboxylic acid ethyl ester; Ethyl 6-bromo-2-indolizinecarboxylate; 2-Indolizinecarboxylic acid, 6-bromo-, ethyl ester; 6-Bromo-2-indolizinecarboxylic acid ethyl ester; Ethyl 6-bromoindolizine-2-carboxylate; 1251014-35-3; Ethyl 6-bromo-1H-pyrrolo[1,2-a]pyridine-2-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 6-Bromoindolizine-2-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to quality supports compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.