Description

3-Boc-6-Oxo-3-Aza-Bicyclo[3.1.1]Heptane is a high-purity, advanced pharmaceutical intermediate featuring a unique bridged bicyclic scaffold. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for constructing novel, conformationally constrained active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of complex molecules targeting central nervous system (CNS) disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel drug candidates, particularly for CNS-targeting therapies.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization programs.
• Protease Inhibitor Synthesis: Employed in the construction of complex molecular architectures for potential protease inhibitor applications.
• Chemical Biology Probes: Serves as a core structure for developing specialized chemical probes to study biological pathways and enzyme functions.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing custom synthesis and process development.
• Academic Research: Utilized in university laboratories for methodological development and the exploration of new synthetic routes involving constrained heterocycles.

Basic Information

Product Name	3-Boc-6-Oxo-3-Aza-Bicyclo[3.1.1]Heptane
CAS No.	1251013-26-9
Molecular Formula	C11H17NO3
Molecular Weight	211.26 g/mol
Synonyms	tert-Butyl 6-oxo-3-azabicyclo[3.1.1]heptane-3-carboxylate; 3-Aza-3-(tert-butoxycarbonyl)bicyclo[3.1.1]heptan-6-one; 3-Boc-3-azabicyclo[3.1.1]heptan-6-one; 3-(tert-Butoxycarbonyl)-3-azabicyclo[3.1.1]heptan-6-one; Bicyclo[3.1.1]heptan-6-one, 3-[(1,1-dimethylethoxy)carbonyl]-3-aza-; 3-Boc-6-oxo-3-azabicyclo[3.1.1]heptane
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is analyzed using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing all relevant specifications are available upon request. We adhere to strict quality management protocols suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.