Description

Racemic-(3As,4S,6As)-2-(tert-Butoxycarbonyl)Octahydrocyclopenta[C]Pyrrole-4-Carboxylic Acid is a sophisticated chiral building block and protected amino acid derivative of significant interest in advanced organic synthesis. Its core value lies in its rigid, bicyclic scaffold and orthogonal protecting groups, which enable the precise construction of complex molecular architectures with defined stereochemistry. This compound is essential for research chemists and process development scientists in the pharmaceutical industry, particularly for the synthesis of novel active pharmaceutical ingredients (APIs), peptide mimetics, and other bioactive compounds targeting the central nervous system and metabolic diseases.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel drug candidates, especially for neurological and metabolic disorders.
• Peptidomimetics Synthesis: Used to construct conformationally restricted peptide analogs to enhance metabolic stability and receptor selectivity.
• Chemical Biology Probes: Serves as a scaffold for developing tool compounds and probes to study enzyme function and protein-protein interactions.
• Asymmetric Catalysis Ligand Precursor: The protected pyrrolidine structure can be elaborated into chiral ligands for asymmetric synthesis.
• Academic & Contract Research: Critical for exploratory organic chemistry and medicinal chemistry programs in academic and CRO (Contract Research Organization) settings.
• Process Chemistry Development: Used in route scouting and optimization for the scalable production of complex target molecules.

Basic Information

Product Name	Racemic-(3As,4S,6As)-2-(tert-Butoxycarbonyl)Octahydrocyclopenta[C]Pyrrole-4-Carboxylic Acid
CAS No.	1251012-45-9
Molecular Formula	C13H21NO4
Molecular Weight	255.31 g/mol
Synonyms	(±)-(3aR,4S,6aS)-2-[(tert-Butoxy)carbonyl]octahydrocyclopenta[c]pyrrole-4-carboxylic Acid; rac-(3aR,4S,6aS)-2-(Boc)octahydrocyclopenta[c]pyrrole-4-carboxylic Acid; 2-Boc-4-carboxyoctahydrocyclopenta[c]pyrrole; (3aS,4S,6aR)-2-(tert-Butoxycarbonyl)octahydro-1H-cyclopenta[c]pyrrole-4-carboxylic Acid (Enantiomer); BOC-Cpp-OH; Cyclopentapyrrolidine-4-carboxylic acid, 2-(1,1-dimethylethoxy)carbonyl-, (3aS,4S,6aR)-rel-; 1H-Cyclopenta[c]pyrrole-4-carboxylic acid, octahydro-2-[(1,1-dimethylethoxy)carbonyl]-, (3aS,4S,6aR)-rel-
EINECS	Contact for details

Quality Control

Our production of Racemic-(3As,4S,6As)-2-(tert-Butoxycarbonyl)Octahydrocyclopenta[C]Pyrrole-4-Carboxylic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and chiral analysis, NMR for structural confirmation, and MS for identity verification. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support development projects requiring material produced under GMP-like conditions for non-clinical studies.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. For long-term storage, consider storing at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	Racemic mixture (50:50 enantiomeric ratio)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.