Description

(2-Bromo-4,5,6,7-Tetrahydro-Benzothiazol-6-Yl)-Carbamic Acid tert-Butyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its functionalized benzothiazole core. This compound is critical for research and development in medicinal chemistry, serving as a versatile building block for the synthesis of novel therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on developing new drug candidates, particularly in areas requiring complex heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Protease Inhibitor Development: The benzothiazole moiety is valuable in constructing molecules that interact with enzyme active sites.
• Kinase Inhibitor Synthesis: Serves as a building block for compounds designed to modulate kinase signaling pathways in oncology and other therapeutic areas.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying biological processes and target validation.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific synthetic routes.

Basic Information

Product Name	(2-Bromo-4,5,6,7-Tetrahydro-Benzothiazol-6-Yl)-Carbamic Acid tert-Butyl Ester
CAS No.	1251009-79-6
Molecular Formula	C₁₂H₁₉BrN₂O₂S
Molecular Weight	335.26 g/mol
Synonyms	tert-Butyl N-(2-bromo-4,5,6,7-tetrahydro-1,3-benzothiazol-6-yl)carbamate; 6-[(tert-Butoxycarbonyl)amino]-2-bromo-4,5,6,7-tetrahydro-1,3-benzothiazole; 2-Bromo-6-((tert-butoxycarbonyl)amino)-4,5,6,7-tetrahydrobenzo[d]thiazole; Boc-6-Amino-2-bromo-4,5,6,7-tetrahydrobenzothiazole; 2-Bromo-6-N-Boc-amino-4,5,6,7-tetrahydrobenzothiazole; 2-Bromo-6-(Boc-amino)-4,5,6,7-tetrahydrobenzothiazole
EINECS	Contact for details

Quality Control

Our production of (2-Bromo-4,5,6,7-Tetrahydro-Benzothiazol-6-Yl)-Carbamic Acid tert-Butyl Ester adheres to stringent quality management protocols. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); containers must be kept tightly sealed to exclude moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.