Description

tert-Butyl n-(2-Azabicyclo[2.1.1]Hexan-1-Ylmethyl)Carbamate is a specialized bicyclic amine derivative, protected with a Boc (tert-butoxycarbonyl) group, which is critical for advanced organic synthesis. This compound serves as a key chiral building block and intermediate in the development of complex pharmaceutical molecules. It is primarily required by research and development organizations and chemical manufacturers in the pharmaceutical and agrochemical sectors for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting neurological and metabolic disorders.
• Agrochemical Research: Used as a building block for developing novel herbicides, fungicides, and insecticides with specific chiral activity.
• Peptidomimetics & PROTACs: The rigid bicyclic scaffold and protected amine make it valuable for constructing peptidomimetics and Proteolysis-Targeting Chimeras (PROTACs).
• Ligand & Catalyst Development: Employed in the research and synthesis of novel chiral ligands and organocatalysts for asymmetric synthesis.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, complex intermediates.

Basic Information

Product Name	tert-Butyl n-(2-Azabicyclo[2.1.1]Hexan-1-Ylmethyl)Carbamate
CAS No.	1250997-46-6
Molecular Formula	C12H22N2O2
Molecular Weight	226.32 g/mol
Synonyms	1-[[(1,1-Dimethylethoxy)carbonyl]amino]methyl]-2-azabicyclo[2.1.1]hexane; 2-Azabicyclo[2.1.1]hexane-1-methanamine, N-BOC-protected; tert-Butyl (2-azabicyclo[2.1.1]hexan-1-ylmethyl)carbamate; BOC-Protected 2-Azabicyclo[2.1.1]hexan-1-ylmethanamine; N-Boc-2-azabicyclo[2.1.1]hexane-1-methanamine; (2-Azabicyclo[2.1.1]hexan-1-ylmethyl)carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl n-(2-Azabicyclo[2.1.1]Hexan-1-Ylmethyl)Carbamate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific project requirements, supporting development under cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.