Description

Racemic 2-Aza-Bicyclo[2.2.2]Octane-2,6-Dicarboxylic Acid 2-tert-Butyl Ester is a high-value, chiral bicyclic building block of significant interest in advanced organic synthesis. This compound serves as a critical intermediate for the development of novel pharmaceuticals and bioactive molecules, particularly those targeting the central nervous system. Research chemists and process development scientists in the pharmaceutical and agrochemical industries rely on this high-purity intermediate to construct complex molecular architectures with precise stereochemistry.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the research and development of new drug candidates, especially neuromodulators and receptor ligands.
• Asymmetric Synthesis: Used as a building block in the construction of complex, stereochemically defined molecules for medicinal chemistry programs.
• Ligand and Catalyst Development: Serves as a precursor for novel chiral ligands and organocatalysts used in enantioselective transformations.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes for studying biological pathways and protein function.
• Agrochemical Research: Intermediate in the development of new, high-performance active ingredients with specific stereochemical requirements.
• Academic Research: A valuable compound for methodological studies in organic synthesis and for exploring new chemical space in university and institutional labs.

Basic Information

Product Name	Racemic 2-Aza-Bicyclo[2.2.2]Octane-2,6-Dicarboxylic Acid 2-tert-Butyl Ester
CAS No.	1250997-05-7
Molecular Formula	C₁₄H₂₁NO₄
Molecular Weight	267.32 g/mol
Synonyms	2-Aza-bicyclo[2.2.2]octane-2,6-dicarboxylic acid, 2-(1,1-dimethylethyl) ester, (±)-form; 2-tert-Butyl 2-azabicyclo[2.2.2]octane-2,6-dicarboxylate; rac-2-(tert-Butoxycarbonyl)-2-azabicyclo[2.2.2]octane-6-carboxylic acid; DL-2-Aza-bicyclo[2.2.2]octane-2,6-dicarboxylic acid 2-tert-butyl ester; Bicyclo[2.2.2]octane, 2-aza-, deriv.; 2-Azabicyclo[2.2.2]octane-2,6-dicarboxylic acid tert-butyl ester (racemic)
EINECS	Contact for details

Quality Control

Our Racemic 2-Aza-Bicyclo[2.2.2]Octane-2,6-Dicarboxylic Acid 2-tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral purity assessment, NMR, and MS for structural confirmation, to ensure it meets the exacting standards required for research and development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (HPLC)	Racemic mixture (50:50 enantiomer ratio)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.