Description

tert-Butyl3-Oxa-8-Azabicyclo[3.2.1]Oct-6-Ene-8-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a complex, functionalized bicyclic scaffold. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral research. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for constructing sophisticated molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates, especially those targeting neurological pathways.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Process Chemistry Development: Serves as a key starting material for optimizing scalable and cost-effective synthetic routes to target molecules.
• CNS Drug Development: Its structural features make it particularly relevant for synthesizing compounds intended to cross the blood-brain barrier.
• Academic Research: Employed in universities and research institutes for methodological studies in organic synthesis and heterocyclic chemistry.
• Contract Manufacturing (CDMO): Supplied to contract development and manufacturing organizations for the production of clinical trial materials.

Basic Information

Product Name	tert-Butyl3-Oxa-8-Azabicyclo[3.2.1]Oct-6-Ene-8-Carboxylate
CAS No.	1250996-94-1
Molecular Formula	C11H17NO3
Molecular Weight	211.26 g/mol
Synonyms	8-Boc-3-oxa-8-azabicyclo[3.2.1]oct-6-ene; tert-Butyl 3-oxa-8-azabicyclo[3.2.1]oct-6-ene-8-carboxylate; 3-Oxa-8-azabicyclo[3.2.1]oct-6-ene-8-carboxylic acid, 1,1-dimethylethyl ester; Bicyclo[3.2.1]oct-6-ene-8-carboxylic acid, 3-oxa-8-aza-, 1,1-dimethylethyl ester; 8-[(tert-Butoxycarbonyl)-3-oxa-8-azabicyclo[3.2.1]oct-6-ene; Boc-3-oxa-8-azanorborn-6-ene
EINECS	Contact for details

Quality Control

Our tert-Butyl3-Oxa-8-Azabicyclo[3.2.1]Oct-6-Ene-8-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and relevant industry standards for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.