Description

tert-Butyl n-{2-Azabicyclo[2.2.1]Heptan-7-Yl}Carbamate is a high-value, protected amine derivative featuring a rigid bicyclic scaffold. This compound is a critical pharmaceutical intermediate and building block in advanced organic synthesis, prized for its unique stereochemistry and functional group compatibility. It is primarily utilized by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for the creation of novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides that require specific stereochemical configurations for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics and Bioactive Molecule Construction: The 2-azabicyclo[2.2.1]heptane core is a valuable scaffold for mimicking peptide structures and designing enzyme inhibitors.
• Academic and Industrial R&D: Essential for medicinal chemistry programs and process chemistry development in contract research and manufacturing organizations (CROs/CMOs).
• Custom Synthesis Starting Material: Provides a protected amine handle for multi-step synthetic routes to complex natural products and fine chemicals.

Basic Information

Item	Details
Product Name	tert-Butyl n-{2-Azabicyclo[2.2.1]Heptan-7-Yl}Carbamate
CAS No.	1250995-45-9
Molecular Formula	C11H20N2O2
Molecular Weight	212.29 g/mol
Synonyms	7-[(tert-Butoxycarbonyl)amino]-2-azabicyclo[2.2.1]heptane; tert-Butyl (7-amino-2-azabicyclo[2.2.1]hept-2-yl)carbamate; 2-Azabicyclo[2.2.1]heptan-7-amine, N-BOC-protected; BOC-2-Azabicyclo[2.2.1]heptan-7-amine; N-Boc-7-amino-2-azabicyclo[2.2.1]heptane; tert-Butyl carbamate derivative of 2-azabicyclo[2.2.1]heptan-7-amine; BOC-Amine of 2-azabicyclo[2.2.1]heptane
EINECS	Contact for details

Quality Control

Our tert-Butyl n-{2-Azabicyclo[2.2.1]Heptan-7-Yl}Carbamate is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity (if applicable), and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.