Description

2-(2-Hydroxymethyl-Piperidin-1-Yl)-1-Thiophen-2-Yl-Ethanone is a high-purity, advanced pharmaceutical intermediate characterized by its piperidine and thiophene heterocyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex molecular architectures. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new drug candidates, especially within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates targeting central nervous system (CNS) disorders, inflammation, and infectious diseases.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Used in the scale-up and optimization of synthetic routes for potential Active Pharmaceutical Ingredients (APIs).
• Chemical Reference Standard: Employed as an analytical standard for quality control and method validation in pharmaceutical analysis.
• Academic & Industrial R&D: Utilized in organic synthesis research to explore new heterocyclic chemistry and develop novel synthetic methodologies.

Basic Information

Product Name	2-(2-Hydroxymethyl-Piperidin-1-Yl)-1-Thiophen-2-Yl-Ethanone
CAS No.	1250898-95-3
Molecular Formula	C13H19NO2S
Molecular Weight	253.36 g/mol
Synonyms	1-(2-Thienyl)-2-[(2-hydroxymethyl-1-piperidinyl)]ethanone; 2-(2-Hydroxymethylpiperidin-1-yl)-1-(thiophen-2-yl)ethanone; 2-(2-Hydroxymethyl-1-piperidinyl)-1-(2-thienyl)ethanone; Ethanone, 1-(2-thienyl)-2-[(2-hydroxymethyl-1-piperidinyl)]-; 2-(2-Hydroxymethylpiperidino)-2'-thienylethanone; 1250898-95-3
EINECS	Contact for details

Quality Control

Our 2-(2-Hydroxymethyl-Piperidin-1-Yl)-1-Thiophen-2-Yl-Ethanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your research and development processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.