Description

5-n-Boc-4,5,6,7-Tetrahydropyrazolo[1,5-A]Pyrazine-2-Carboxylic Acid Ethyl Ester is a high-purity, advanced pharmaceutical intermediate crucial for modern drug discovery and development. This compound serves as a key building block in the synthesis of complex heterocyclic molecules, enabling the creation of novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies focused on developing new active pharmaceutical ingredients (APIs), particularly in areas requiring sophisticated nitrogen-containing scaffolds.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders and oncology.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Heterocyclic Compound Synthesis: Serves as a foundational unit for constructing complex fused pyrazolo-pyrazine ring systems with potential biological activity.
• Proteolysis Targeting Chimera (PROTAC) Development: Can be utilized in the synthesis of linker components or warhead conjugates for targeted protein degradation platforms.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting pharmaceutical clients with custom synthesis and scale-up projects.
• Academic Research: Employed in university and institutional labs for methodological studies in organic synthesis and heterocyclic chemistry.

Basic Information

Item	Detail
Product Name	5-n-Boc-4,5,6,7-Tetrahydropyrazolo[1,5-A]Pyrazine-2-Carboxylic Acid Ethyl Ester
CAS No.	1250443-97-0
Molecular Formula	C15H21N3O4
Molecular Weight	307.35 g/mol
Synonyms	Ethyl 5-[(tert-butoxy)carbonyl]-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxylate; 5-(tert-Butoxycarbonyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxylic acid ethyl ester; 5-Boc-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-2-carboxylic acid ethyl ester; BOC-Pyrazolo-pyrazine ethyl ester; 1250443-97-0; tert-Butyl 2-(ethoxycarbonyl)-4,5,6,7-tetrahydropyrazolo[1,5-a]pyrazine-5-carboxylate
EINECS	Contact for details

Quality Control

Our 5-n-Boc-4,5,6,7-Tetrahydropyrazolo[1,5-A]Pyrazine-2-Carboxylic Acid Ethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are available upon request to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Due to its nature as a strong acid/organic solvent-compatible compound, it should be kept away from incompatible materials. For long-term storage, consider inert atmosphere conditions to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.