Description

7-Bromo-5-Fluoro-1,2,3,4-Tetrahydro-Isoquinoline is a high-value, multi-functional heterocyclic building block essential for modern synthetic chemistry. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and advanced materials. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce halogenated, fused-ring systems into their molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of potential drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging the biological activity of the halogenated isoquinoline scaffold.
• Material Science: Acts as a building block for creating specialized ligands, catalysts, and organic electronic materials.
• Chemical Biology: Employed in the design and synthesis of molecular probes and tool compounds for studying biological pathways.
• Custom Synthesis: A versatile starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for clients.
• Academic Research: Utilized in universities and research institutes for methodological development and exploring new chemical spaces.

Basic Information

Product Name	7-Bromo-5-Fluoro-1,2,3,4-Tetrahydro-Isoquinoline
CAS No.	1250064-89-1
Molecular Formula	C9H9BrFN
Molecular Weight	230.08 g/mol
Synonyms	7-Bromo-5-fluoro-1,2,3,4-tetrahydroisoquinoline; 5-Fluoro-7-bromo-1,2,3,4-tetrahydroisoquinoline; 1,2,3,4-Tetrahydro-7-bromo-5-fluoro-isoquinoline; 7-Bromo-5-fluoro-3,4-dihydro-1H-isoquinoline; 1250064-89-1; 7-Br-5-F-THIQ
EINECS	Contact for details

Quality Control

Our 7-Bromo-5-Fluoro-1,2,3,4-Tetrahydro-Isoquinoline is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all specifications and test results. We support cGMP and ISO standards for pharmaceutical and industrial applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if possible. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.