Description

Methyl 2-Chloro-2-(Thiophen-3-Yl)Acetate is a high-purity synthetic intermediate featuring a reactive α-chloroacetate ester group attached to a thiophene heterocycle. This unique structure makes it a versatile building block for the synthesis of more complex molecules in advanced research and development. It is primarily needed by pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional compounds.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, especially those targeting the central nervous system or possessing anti-inflammatory properties.
• Agrochemical Synthesis: Serves as a building block for developing new herbicides, fungicides, or insecticides with novel modes of action.
• Material Science Research: Used in the development of organic semiconductors, conductive polymers, or advanced ligands for catalysis due to the electron-rich thiophene moiety.
• Chemical Biology Probes: Employed in creating tagged molecules or activity-based probes for studying biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring functionalized thiophene derivatives.

Basic Information

Product Name	Methyl 2-Chloro-2-(Thiophen-3-Yl)Acetate
CAS No.	1249784-85-7
Molecular Formula	C7H7ClO2S
Molecular Weight	190.65 g/mol
Synonyms	Methyl 2-chloro-2-(3-thienyl)acetate; 2-Chloro-2-(thiophen-3-yl)acetic acid methyl ester; Methyl α-chloro-3-thiopheneacetate; 3-Thiopheneacetic acid, α-chloro-, methyl ester; (3-Thienyl)chloroacetic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 2-Chloro-2-(Thiophen-3-Yl)Acetate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We employ advanced analytical techniques including HPLC, GC, NMR, and IR spectroscopy for comprehensive characterization and impurity profiling. A Certificate of Analysis (COA) detailing purity, identity, and specific test results is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.