Description

1-(2-Fluorophenyl)Cyclopropan-1-Ol is a high-value fluorinated cyclopropanol derivative, serving as a critical chiral building block and synthetic intermediate in advanced organic synthesis. Its unique structure, featuring a fluorinated aromatic ring fused with a strained cyclopropanol moiety, enables precise molecular modifications essential for developing novel compounds with targeted properties. This intermediate is primarily sought by research and development teams in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, process development, and the creation of new active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Used in the construction of novel herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioactivity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of advanced organic materials and liquid crystals, where the fluorophenyl group influences mesomorphic and electronic properties.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic chemistry, including ring-opening reactions and cross-coupling protocols.

Basic Information

Product Name	1-(2-Fluorophenyl)Cyclopropan-1-Ol
CAS No.	1249293-03-5
Molecular Formula	C9H9FO
Molecular Weight	152.17 g/mol
Synonyms	1-(2-Fluorophenyl)cyclopropanol; (2-Fluorophenyl)cyclopropylmethanol; 2-Fluorophenylcyclopropanol; α-(2-Fluorophenyl)cyclopropanemethanol; 1-(o-Fluorophenyl)cyclopropan-1-ol; 2-Fluorobenzenecyclopropanol; Cyclopropanol, 1-(2-fluorophenyl)-; 1249293-03-5
EINECS	Contact for details

Quality Control

Every batch of 1-(2-Fluorophenyl)Cyclopropan-1-Ol is manufactured under strict quality management systems. We provide comprehensive analytical documentation to ensure traceability and consistency for your critical R&D and scale-up processes. Our standard quality commitment includes rigorous purity verification by HPLC/GC, chiral purity analysis, and control of specified impurities. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (Typical)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.