Description

Ethyl 3-Hydroxytetrahydrothiophene-3-Carboxylate is a high-purity, functionalized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a versatile chiral synthon, enabling the construction of complex molecular architectures with precise stereochemistry. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and antiviral research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its heterocyclic thiophene core.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Investigated as a monomer or additive for specialty polymers with unique electronic or mechanical properties.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and discovery chemistry projects.
• Custom Synthesis: A starting point for the bespoke manufacturing of complex, high-value fine chemicals for various industrial applications.

Basic Information

Product Name	Ethyl 3-Hydroxytetrahydrothiophene-3-Carboxylate
CAS No.	1248642-62-7
Molecular Formula	C7H12O3S
Molecular Weight	176.23 g/mol
Synonyms	Ethyl 3-Hydroxytetrahydrothiophene-3-carboxylate; 3-Hydroxytetrahydrothiophene-3-carboxylic Acid Ethyl Ester; Tetrahydro-3-hydroxy-3-thiophenecarboxylic Acid Ethyl Ester; 3-Thiophenecarboxylic acid, tetrahydro-3-hydroxy-, ethyl ester; Ethyl 3-hydroxy-2,5-dihydrothiophene-3-carboxylate (tautomer).
EINECS	Contact for details

Quality Control

Our Ethyl 3-Hydroxytetrahydrothiophene-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity assessment, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.