Description

4-(1-Methyl-4-Piperidyl)Phenylboronic Acid Pinacol Ester is a high-purity, advanced pharmaceutical intermediate featuring a protected boronic acid functional group. This compound is critical for enabling efficient Suzuki-Miyaura cross-coupling reactions, a cornerstone methodology in modern medicinal chemistry for constructing complex biaryl scaffolds. It is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and drug candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those targeting the central nervous system (CNS).
• Suzuki-Miyaura Cross-Coupling Reagent: Enables the formation of carbon-carbon bonds between aryl halides and aryl boronic acids/esters under mild conditions.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Serves as a monomer or precursor in the creation of organic electronic materials and functional polymers.
• Chemical Biology Probes: Facilitates the synthesis of labeled compounds and probes for studying biological pathways and target engagement.
• Process Chemistry & Scale-up: Employed in the development of robust, scalable synthetic routes for commercial production.

Basic Information

Product Name	4-(1-Methyl-4-Piperidyl)Phenylboronic Acid Pinacol Ester
CAS No.	1247000-92-5
Molecular Formula	C18H28BNO2
Molecular Weight	301.24 g/mol
Synonyms	4-(1-Methylpiperidin-4-yl)phenylboronic acid pinacol ester; 4-(N-Methyl-4-piperidyl)benzeneboronic acid pinacol ester; 4-(1-Methyl-4-piperidinyl)benzeneboronic acid pinacol ester; 4-(1-Methylpiperidin-4-yl)benzeneboronic acid pinacol ester; 4-(N-Methylpiperidin-4-yl)phenylboronic acid pinacol ester; 4-(1-Methyl-4-piperidyl)phenyl-B(pin); (4-(1-Methylpiperidin-4-yl)phenyl)boronic acid pinacol ester
EINECS	Contact for details

Quality Control

Our 4-(1-Methyl-4-Piperidyl)Phenylboronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when opening to prevent degradation. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.