Description

(E)-n-(Naphthalen-1-Ylmethyl)-3-Phenyl-n-(Trideuteriomethyl)Prop-2-En-1-Amine:Hydrochloride CAS NO 1246833-81-7 is a deuterated organic compound supplied as a hydrochloride salt, offering enhanced stability and unique properties for advanced research applications. Its value lies in providing a high-purity, isotopically labeled building block crucial for mechanistic studies and the development of novel materials. This product is primarily needed by researchers and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for applications in medicinal chemistry, metabolic studies, and analytical method development.

Application

• Pharmaceutical Intermediate: Serves as a key deuterated synthon in the research and development of new active pharmaceutical ingredients (APIs), leveraging kinetic isotope effects.
• Metabolic Pathway Tracer: Used in drug metabolism and pharmacokinetics (DMPK) studies to track and analyze metabolic pathways and stability.
• Medicinal Chemistry Research: Acts as a building block for creating deuterium-labeled analogs of lead compounds to improve metabolic stability and patent life.
• Analytical Reference Standard: Employed as a high-purity internal standard or calibrant in advanced analytical techniques like LC-MS and NMR for accurate quantification.
• Agrochemical Development: Utilized in the synthesis of novel, isotopically labeled crop protection agents for environmental fate and residue studies.
• Material Science Research: Investigated for its potential in creating organic semiconductors or specialty polymers with tailored electronic properties.

Basic Information

Product Name	(E)-n-(Naphthalen-1-Ylmethyl)-3-Phenyl-n-(Trideuteriomethyl)Prop-2-En-1-Amine:Hydrochloride
CAS No.	1246833-81-7
Molecular Formula	C21H20D3ClN
Molecular Weight	321.89 g/mol
Synonyms	(E)-N-(1-Naphthylmethyl)-3-phenyl-N-(trideuteriomethyl)prop-2-en-1-amine hydrochloride; N-[(1E)-3-Phenyl-2-propen-1-yl]-N-(trideuteriomethyl)-1-naphthalenemethanamine hydrochloride; Deuterated Naftifine Intermediate; (E)-N-(Naphthalen-1-ylmethyl)-β-methyl-N-(trideuteriomethyl)styrylamine hydrochloride; 1-Naphthalenemethanamine, N-[(1E)-3-phenyl-2-propen-1-yl]-N-(trideuteriomethyl)-, hydrochloride; Naftifine-d3 Hydrochloride (potential analog)
EINECS	Contact for details

Quality Control

Our (E)-n-(Naphthalen-1-Ylmethyl)-3-Phenyl-n-(Trideuteriomethyl)Prop-2-En-1-Amine:Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity, isotopic enrichment, and identity confirmation. Standard specifications are verified by techniques including HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profile is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.