Description

Curcumin-D6 is a stable isotope-labeled analog of the natural polyphenol curcumin, where six hydrogen atoms are replaced by deuterium. This compound is essential as an internal standard in quantitative mass spectrometry, ensuring the highest accuracy and reliability in analytical measurements. It is a critical tool for researchers and quality control laboratories in the pharmaceutical, nutraceutical, and food science industries who require precise quantification of curcuminoids in complex matrices.

Application

• Internal Standard for LC-MS/MS and GC-MS analysis of curcumin and related curcuminoids.
• Bioavailability and pharmacokinetic studies in pharmaceutical and clinical research.
• Metabolic pathway tracing and biomarker discovery in biomedical research.
• Quality control and assay validation for curcumin-based dietary supplements and extracts.
• Method development and validation in analytical chemistry laboratories.
• Stability studies and degradation product analysis of curcumin formulations.

Basic Information

Product Name	Curcumin-D6
CAS No.	1246833-26-0
Molecular Formula	C21H14D6O6
Molecular Weight	374.40 g/mol
Synonyms	(1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dione-D6; Deuterated Curcumin; Curcumin (Hexadeuterated); Curcumin-d6; Curcumin D6; 1,7-Bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione-d6; Difluoromethane-d2
EINECS	Contact for details

Quality Control

Our Curcumin-D6 is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and isotopic enrichment. Certificates of Analysis (COA) detailing purity, isotopic purity (D-enrichment), and analytical data are provided with every shipment to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing at 2-8°C under inert atmosphere to ensure maximum stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98.0 atom % D
Chemical Purity (NMR)	Conforms
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.