Description

n-Methyl-D3-o-Phenylenediamine is a deuterated derivative of o-phenylenediamine, specifically labeled with three deuterium atoms on the methyl group. This compound is of significant value as a stable isotope-labeled internal standard in analytical chemistry, particularly for mass spectrometry, ensuring precise quantification and method validation. It is essential for researchers and quality control laboratories in the pharmaceutical, agrochemical, and environmental testing sectors who require high-purity reference materials for trace analysis.

Application

• Used as a stable isotope-labeled internal standard (SIL-IS) in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) for accurate quantification.
• Critical for method development and validation in pharmaceutical impurity profiling and metabolite identification studies.
• Employed in environmental analysis for tracing and quantifying aromatic amine pollutants and their degradation products.
• Facilitates metabolomics research by serving as a labeled analog in pathway analysis.
• Acts as a specialized building block in the synthesis of deuterated dyes, polymers, or complex organic molecules for research purposes.
• Supports forensic and toxicological analysis where precise measurement of amine-based compounds is required.

Basic Information

Product Name	n-Methyl-D3-o-Phenylenediamine
CAS No.	1246820-22-3
Molecular Formula	C7H7D3N2
Molecular Weight	125.18 g/mol
Synonyms	N-Methyl-1,2-benzenediamine-d3; 2-Amino-N-methyl-d3-aniline; 1,2-Diamino-3-methyl-d3-benzene; o-(Methyl-d3-amino)aniline; Deuterated N-Methyl-o-phenylenediamine; N-Methyl-d3-1,2-phenylenediamine; [Methyl-d3]-1,2-benzenediamine
EINECS	Contact for details

Quality Control

Every batch of n-Methyl-D3-o-Phenylenediamine is produced and tested under strict quality management systems. We ensure high chemical purity and isotopic enrichment suitable for sensitive analytical applications. A comprehensive Certificate of Analysis (COA) detailing purity (by HPLC/NMR), isotopic purity (D-content), and identity confirmation is provided with each shipment to guarantee reliable and reproducible performance in your laboratory.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) to minimize oxidation and degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to light brown crystalline powder or solid
Identification (IR / NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.