Description

1,5-Dimethyl-2-Phenyl-4-(Trideuteriomethylamino)Pyrazol-3-One CAS NO 1246820-06-3 is a deuterated derivative of a pyrazolone-based compound, offering a stable isotopic label for advanced research and development. This compound is critical for applications requiring precise molecular tracking and metabolic stability studies due to the incorporation of deuterium atoms. It is primarily utilized by pharmaceutical researchers, analytical chemists, and material scientists working on drug discovery, pharmacokinetics, and high-performance material synthesis.

Application

• Pharmaceutical Research & Development: As a stable isotope-labeled internal standard for accurate quantification in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) bioanalytical methods.
• Drug Metabolism and Pharmacokinetics (DMPK) Studies: Used to trace the metabolic pathways and assess the stability of lead compounds, aiding in the design of drugs with improved efficacy and safety profiles.
• Analytical Chemistry: Serves as a critical reference material for method development and validation in forensic, clinical, and environmental testing laboratories.
• Material Science: Potential use in the synthesis of specialized organic materials and ligands where isotopic purity can influence physical or electronic properties.
• Chemical Synthesis: Acts as a building block or intermediate in the synthesis of more complex deuterated molecules for various research purposes.

Basic Information

Product Name	1,5-Dimethyl-2-Phenyl-4-(Trideuteriomethylamino)Pyrazol-3-One
CAS No.	1246820-06-3
Molecular Formula	C₁₂H₁₂D₃N₃O
Molecular Weight	217.27 g/mol
Synonyms	4-(Trideuteriomethylamino)-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one; 1,5-Dimethyl-2-phenyl-4-((methyl-d3)amino)-1H-pyrazol-3(2H)-one; Deuterated Antipyrine Derivative; d3-Aminopyrine; 4-(Methyl-d3-amino)antipyrine; N-(Trideuteriomethyl)-1,5-dimethyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazole-4-carboxamide (related); [d3]-4-Aminoantipyrine
EINECS	Contact for details

Quality Control

Our deuterated chemicals are produced under strict quality control protocols to ensure high isotopic and chemical purity, essential for sensitive analytical applications. Each batch is characterized using advanced techniques including NMR (¹H, ²H) and High-Resolution Mass Spectrometry (HRMS). A comprehensive Certificate of Analysis (COA) detailing purity, isotopic enrichment, and impurity profile is provided with every shipment to support your regulatory and research documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment (²H NMR)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.