Description

Rac 4-Azido Deprenyl-D3 is a deuterated and azido-functionalized derivative of the selegiline molecule, designed for advanced research and development applications. This compound is particularly valuable as a chemical probe or a synthetic intermediate for creating labeled analogs in pharmacological and neurochemical studies. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and contract research organizations (CROs) focused on neuroscience, metabolism, and analytical method development.

Application

• Pharmacological Research: Used as a biochemical tool to study enzyme inhibition mechanisms, particularly related to monoamine oxidase (MAO).
• Metabolic Pathway Tracing: The deuterium (D3) label enables its use in mass spectrometry-based studies for tracking drug metabolism and pharmacokinetics (DMPK).
• Chemical Biology Probe: The azido group allows for bioorthogonal conjugation (e.g., click chemistry) to create fluorescent or affinity-tagged probes for target identification.
• Reference Standard: Serves as a critical certified reference material (CRM) for the analytical validation and quantification of related compounds.
• Synthetic Intermediate: A key building block in the multi-step synthesis of novel, isotopically labeled pharmaceutical candidates for preclinical development.

Basic Information

Product Name	Rac 4-Azido Deprenyl-D3
CAS No.	1246819-62-4
Molecular Formula	C13H14D3N4
Molecular Weight	226.31 g/mol
Synonyms	(±)-N-Methyl-N-(1-phenylpropan-2-yl)-4-azidoprop-2-yn-1-amine-d3; 4-Azido-N-methyl-N-(1-phenylpropan-2-yl)prop-2-yn-1-amine-d3; Rac-4-Azidodeprenyl-d3; Deuterated 4-Azido Deprenyl; Selegiline Azide Derivative-d3; DL-4-Azido Deprenyl-D3
EINECS	Contact for details

Quality Control

Every batch of Rac 4-Azido Deprenyl-D3 is manufactured under strict quality management systems and undergoes comprehensive analytical characterization. We guarantee high chemical and isotopic purity, verified by advanced techniques including NMR, HPLC, and LC-MS. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity (typically ≥95% by HPLC), isotopic enrichment (D3), and other critical specifications to ensure reproducible results for your research.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere for long-term stability. This compound is light-sensitive (store away from light) and should be handled under controlled conditions to prevent degradation. Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Isotopic Purity (D3)	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.