Description

ε-Aminocaproic Acid-D10 Hydrochloride is a high-purity, deuterium-labeled derivative of the antifibrinolytic agent aminocaproic acid. This stable isotope-labeled compound is essential for quantitative bioanalytical studies, serving as a critical internal standard in mass spectrometry to ensure accurate pharmacokinetic and metabolic profiling. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions engaged in advanced drug development and clinical research.

Application

• Internal Standard for LC-MS/MS Analysis: Provides precise quantification of aminocaproic acid in complex biological matrices like plasma, serum, and urine.
• Drug Metabolism and Pharmacokinetics (DMPK) Studies: Enables accurate tracking of drug absorption, distribution, metabolism, and excretion (ADME) for new chemical entities.
• Clinical Research and Therapeutic Drug Monitoring (TDM): Used in developing and validating robust assays to monitor drug concentrations in patients.
• Biomarker Research: Facilitates the precise measurement of endogenous metabolites in pathway analysis and disease state investigations.
• Pharmaceutical Quality Control: Supports method development for impurity profiling and stability testing of drug substances and products.
• Forensic and Toxicology Analysis: Aids in the confirmatory analysis of aminocaproic acid in forensic applications.

Basic Information

Product Name	ε-Aminocaproic Acid-D10 Hydrochloride
CAS No.	1246819-49-7
Molecular Formula	C6D10ClNO2 • HCl
Molecular Weight	203.13 g/mol (approx.)
Synonyms	6-Aminohexanoic Acid-D10 Hydrochloride; 6-Amino-D10-caproic Acid Hydrochloride; EACA-D10 HCl; (6-Amino-D10-hexanoic acid) hydrochloride; Amino-D10-caproic Acid HCl; 6-Aminohexanoic-1,2,3,4,5,6,6,6-D8, 1,2,3,4,5-D5 Acid Hydrochloride; Deuterated Aminocaproic Acid Hydrochloride; Stable Isotope Labeled Aminocaproic Acid HCl
EINECS	Contact for details

Quality Control

Every batch of ε-Aminocaproic Acid-D10 Hydrochloride is manufactured and analyzed under strict quality management systems. We guarantee high chemical and isotopic purity, with comprehensive testing including assay, isotopic enrichment (D10), and identification. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with specifications for use as an internal standard.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. Handle under an inert atmosphere if prolonged exposure is anticipated during use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Enrichment	≥ 98 atom % D
Chemical Purity (NMR)	Conforms
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.