Description

3-(2,2,3,3,4,4,5,5,6,6-Decadeuteriopiperidin-1-Yl)-1-(4-Ethylphenyl)-2-Methylpropan-1-One:Hydrochloride is a deuterated piperidine derivative, specifically designed as a stable isotope-labeled compound. This product is crucial for research and development in analytical chemistry, where it serves as an internal standard for mass spectrometry, enabling precise quantification and metabolic studies. It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and academic institutions focused on drug discovery, pharmacokinetics, and bioanalytical method development.

Application

• Internal Standard for LC-MS/MS: Used as a quantitative reference standard in liquid chromatography-tandem mass spectrometry for bioanalytical assays.
• Drug Metabolism and Pharmacokinetics (DMPK): Facilitates the study of absorption, distribution, metabolism, and excretion (ADME) of pharmaceutical compounds.
• Stable Isotope Labeling: Acts as a labeled analog in metabolic pathway tracing and proteomics research.
• Pharmaceutical Impurity Profiling: Assists in the identification and quantification of process-related impurities or degradants.
• Forensic and Clinical Toxicology: Employed in confirmatory testing and precise measurement of target analytes in complex biological matrices.
• Reference Material for Method Validation: Provides a certified standard for validating analytical methods in compliance with GLP and ICH guidelines.

Basic Information

Product Name	3-(2,2,3,3,4,4,5,5,6,6-Decadeuteriopiperidin-1-Yl)-1-(4-Ethylphenyl)-2-Methylpropan-1-One:Hydrochloride
CAS No.	1246819-46-4
Molecular Formula	C17H18D10ClNO
Molecular Weight	Contact for details
Synonyms	1-(4-Ethylphenyl)-2-methyl-1-[1-(2,2,3,3,4,4,5,5,6,6-decadeuteriopiperidinyl)]propan-1-one hydrochloride; Deuterated Piperidine Derivative; 3-(Decadeuteriopiperidin-1-yl)-1-(4-ethylphenyl)-2-methylpropan-1-one hydrochloride; 1246819-46-4; Stable Isotope-Labeled Internal Standard; D10-Labeled Piperidine Compound; (4-Ethylphenyl)-2-methyl-1-(piperidin-1-yl-D10)propan-1-one HCl
EINECS	Contact for details

Quality Control

Our deuterated compounds are produced under strict quality management systems to ensure high isotopic purity and chemical integrity. Each batch undergoes rigorous analytical testing, including NMR, HPLC, and mass spectrometry, to confirm identity, chemical purity, and isotopic enrichment. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer requirements for research or regulatory submission.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the product should be handled in a dry environment and the container kept sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.