Description

Dideuterio-(2,3,3-Trideuteriooxiran-2-Yl)Methanol is a deuterated derivative of glycidol, a versatile epoxide building block where specific hydrogen atoms are replaced with deuterium. This isotopic labeling is critical for applications requiring enhanced molecular stability, precise metabolic tracing, or altered spectroscopic properties. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity, isotopically labeled intermediates for synthesis, analytical standards, and mechanistic studies.

Application

• Pharmaceutical Research & Development: As a deuterated synthon for creating isotopically labeled active pharmaceutical ingredients (APIs) to study drug metabolism, pharmacokinetics (DMPK), and to potentially improve metabolic stability.
• Analytical Chemistry & Spectroscopy: Serving as an internal standard or reference material in quantitative mass spectrometry (MS) and nuclear magnetic resonance (NMR) spectroscopy due to its distinct isotopic signature.
• Mechanistic & Kinetic Studies: Employed as a tracer to elucidate complex reaction mechanisms and measure kinetic isotope effects (KIEs) in organic and enzymatic synthesis.
• Agrochemical Development: Used in the synthesis of novel, labeled agrochemicals for environmental fate studies and residue analysis.
• Advanced Material Science: As a specialized monomer or cross-linking agent in the synthesis of polymers with tailored properties for electronics or specialty coatings.
• Contract Research & Manufacturing (CRMO): Supplied to service organizations that require high-purity, custom deuterated compounds for client projects.

Basic Information

Product Name	Dideuterio-(2,3,3-Trideuteriooxiran-2-Yl)Methanol
CAS No.	1246819-20-4
Molecular Formula	C3D5HO2
Molecular Weight	95.12 g/mol (deuterated form)
Synonyms	(2,3,3-2H3)Oxiranemethanol-1,1-2H2; [1,1-2H2;2,3,3-2H3]Glycidol; Deuterated Glycidol (d5); Glycidol-d5; 2-(Hydroxymethyl-d2)oxirane-d3; 2,3-Epoxy-1-propanol-d5; Oxiranemethanol-d5
EINECS	Contact for details

Quality Control

Our deuterated chemicals are produced and controlled under a strict quality management system. Each batch of Dideuterio-(2,3,3-Trideuteriooxiran-2-Yl)Methanol undergoes rigorous analytical testing, including NMR and GC-MS or HPLC, to confirm isotopic purity (D-enrichment), chemical purity, and identity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (NMR)	Conforms to structure
Chemical Purity (GC/HPLC)	≥ 98.0%
Isotopic Purity (Deuterium Enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.